产品货号：
Z34543
中文名称：
LAG3抗体
英文名称：
Anti-LAG3 Antibody (Clone#2G8)
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LAG3 Antibody (Clone#2G8) |
| 指标别名 | CD223;FDC;LAG3;LAG-3;lymphocyte activation gene 3;Protein FDC |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,IHC,ICC,IF,FCM |
| 基因名称 | LAG3 |
| 克隆号 | 2G8 |
| 抗体来源 | Mouse |
| 免疫原 | LAG-3 antibody was raised against the extracellular domain of human LAG-3 |
| 计算分子量 | 57kDa |
| 成分 | LAG-3 Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol. |
| 纯化方式 | LAG-3 Antibody is supplied as protein A purified IgG1. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The lymphocyte activation gene-3 (LAG3) is a member of the immunoglobulin superfamily and binds MHC class II with high affinity (1),negatively regulating T-cell function and homeostasis (2).It is expressed in B,T,and NK cells,monocytes,and dendritic cells (3),and acts to regulate T cell expansion (4).LAG3 is also an important immune checkpoint protein,with anti-LAG3 antibodies activating T effector cells and affecting regulatory T cell functions.Furthermore LAG3 appears to act in a synergistic fashion with PD-1/PD-L1,suggesting that a dual antibody approach may prove useful in cancer immunotherapy. |
| Uniprot ID | P18627 |
| 基因名全称 | Lymphocyte activating 3 |
| 蛋白名全称 | Lymphocyte activating 3 |
| 推荐稀释比 | LAG-3 antibody can be used for ELISA starting at 0.25μg/mL.For Western blot start at 0.25μg/mL.For Immunocytochemistry start at 1μg/mL.For Immunofluorescence start at 10μg/mL.For Immunohistochemistry start at 5μg/mL.For Flow Cytometry start at 1μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples;Immunocytochemistry in human samples;Immunofluorescence in human samples and Flow Cytometry in human samples.All other applications and species not yet tested. |
相关搜索：LAG3抗体，LAG3单抗，Anti-LAG3 Antibody (Clone#2G8)